An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

Cognitive decline associated with aging is caused by the loss of cholinergic nerve supply to the hippocampus of our brain. Since the hippocampus is the center of learning and memory, a reduction in ...

In vivo protein expression includes cloning a gene of interest with the essential control elements into an expression vector, and then transforming the vector into an easily grown organism or cell ...

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease. The findings, ...

ALBUQUERQUE, NM and MEMPHIS, TN – November 25, 2025 – Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms ...

In a recent study published in the journal Nature Biotechnology, researchers describe the pA regulator system based on a ribonucleic acid (RNA)-based switch to regulate mammalian gene expression by ...

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a ...