Long non-coding RNAs (lncRNAs) represent a diverse class of transcripts that, despite lacking protein‐coding capacity, play critical roles in the regulation of gene expression. Their functions span ...

“There is strong debate in the scientific community on whether the thousands of long non-coding RNAs generated from our genomes are functional or simply byproducts of a noisy transcriptional machinery ...

A new study identifies PTCHD1-AS as a key non-coding gene that shapes social and repetitive behaviors in autism without affecting cognition.

A long-overlooked stretch of the human genome appears to play a distinct role in shaping the social and stereotypic ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Researchers have pinpointed a long non-coding gene that plays a distinct role in the social and stereotypic repetitive ...

Long Noncoding RNAs (LncRNAs) are proven to be critical in cancer biology playing a significant role in tumor formation and progression. In contrast to protein coding RNAs, lncRNAs can neither be ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

What is the dark genome: The 98% of DNA that doesn't code for proteins is now known to play key roles in regulating genes, influencing traits, and impacting disease. Why it matters: Discoveries in the ...